CATH Domain 5lktA01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Histone acetyltransferase p300

Enzyme Information

2.3.1.48	Histone acetyltransferase. based on mapping to UniProt Q09472 Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. -!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-	Transferring groups other than amino-acyl groups. based on mapping to UniProt Q09472

UniProtKB Entries (1)

EP300_HUMAN

Homo sapiens

Histone acetyltransferase p300

PDB Structure

PDB	5LKT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of p300 in complex with acyl-CoA variants. Kaczmarska, Z., Ortega, E., Goudarzi, A., Huang, H., Kim, S., Marquez, J.A., Zhao, Y., Khochbin, S., Panne, D. Nat. Chem. Biol.