CATH Domain 5le1A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.15	Metallo-beta-lactamase; Chain A
	3.60.15.10	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family	Class B metallo-beta-lactamase

Enzyme Information

UniProtKB Entries (1)

Q9K2N0_PSEAI

Pseudomonas aeruginosa

Beta-lactamase class B VIM-2

PDB Structure

PDB	5LE1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	NMR-filtered virtual screening leads to non-metal chelating metallo-beta-lactamase inhibitors. Li, G.B., Abboud, M.I., Brem, J., Someya, H., Lohans, C.T., Yang, S.Y., Spencer, J., Wareham, D.W., McDonough, M.A., Schofield, C.J. Chem Sci