CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.58.1880
Functional Family REST corepressor 1

Enzyme Information

UniProtKB Entries (1)

O60341
KDM1A_HUMAN
Homo sapiens
Lysine-specific histone demethylase 1A

PDB Structure

PDB 5L3D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Pilotto, S., Speranzini, V., Marabelli, C., Rusconi, F., Toffolo, E., Grillo, B., Battaglioli, E., Mattevi, A.
Hum.Mol.Genet.
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