CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.80 | ATP synthase, gamma subunit, helix hairpin domain |
Domain Context
CATH Clusters
| Superfamily | ATP synthase, gamma subunit, helix hairpin domain |
| Functional Family | Lysine-specific histone demethylase 1A |
Enzyme Information
| 1.-.-.- |
Oxidoreductases.
based on mapping to UniProt O60341
|
UniProtKB Entries (1)
| O60341 |
KDM1A_HUMAN
Homo sapiens
Lysine-specific histone demethylase 1A
|
PDB Structure
| PDB | 5L3D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Hum.Mol.Genet.
|