CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | Arylesterase |
Enzyme Information
| 3.1.1.2 |
Arylesterase.
based on mapping to UniProt B5BLW5
A phenyl acetate + H(2)O = a phenol + acetate.
-!- Acts on many phenolic esters. -!- It is likely that the three forms of human paraoxonase are lactonases rather than aromatic esterases. -!- The natural substrates of the paraoxonases are lactones, with (+-)-5- hydroxy-6E,8Z,11Z,4Z-eicostetraenoic-acid 1,5-lactone being the best substrate.
|
| 3.1.8.1 |
Aryldialkylphosphatase.
based on mapping to UniProt B5BLW5
An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol.
-!- Acts on organophosphorus compounds (such as paraoxon) including esters of phosphonic and phosphinic acids. -!- Inhibited by chelating agents. -!- Previously regarded as identical with EC 3.1.1.2.
|
UniProtKB Entries (1)
| B5BLW5 |
ARE_SACSO
Saccharolobus solfataricus
Arylesterase
|
PDB Structure
| PDB | 5L2P |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of arylesterase
To Be Published
|