CATH Domain 5kxaA04

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.570	Extracellular Endonuclease; Chain A
	3.40.570.10	Extracellular Endonuclease, subunit A

Superfamily	Extracellular Endonuclease, subunit A
Functional Family	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

3.1.4.39

Alkylglycerophosphoethanolamine phosphodiesterase.

based on mapping to UniProt Q13822

1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.

-!- Also acts on acyl and choline analogs.

ENPP2_HUMAN

Homo sapiens

Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

PDB	5KXA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis. Bain, G., Shannon, K.E., Huang, F., Darlington, J., Goulet, L., Prodanovich, P., Ma, G.L., Santini, A.M., Stein, A.J., Lonergan, D., King, C.D., Calderon, I., Lai, A., Hutchinson, J.H., Evans, J.F. J. Pharmacol. Exp. Ther.