CATH Domain 5kreA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1820	alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily	alpha/beta hydrolase
Functional Family	lysophospholipase-like protein 1

Enzyme Information

3.1.2.-

Thiolester hydrolases.

based on mapping to UniProt Q5VWZ2

UniProtKB Entries (1)

LYPL1_HUMAN

Homo sapiens

Lysophospholipase-like protein 1

PDB Structure

PDB	5KRE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. Ahn, K., Boehm, M., Brown, M.F., Calloway, J., Che, Y., Chen, J., Fennell, K.F., Geoghegan, K.F., Gilbert, A.M., Gutierrez, J.A., Kalgutkar, A.S., Lanba, A., Limberakis, C., Magee, T.V., O'Doherty, I., Oliver, R., Pabst, B., Pandit, J., Parris, K., Pfefferkorn, J.A., Rolph, T.P., Patel, R., Schuff, B., Shanmugasundaram, V., Starr, J.T., Varghese, A.H., Vera, N.B., Vernochet, C., Yan, J. Acs Chem.Biol.