CATH Classification

Domain Context

CATH Clusters

Superfamily SOS response associated peptidase-like
Functional Family Abasic site processing protein HMCES

Enzyme Information

3.1.25.-
Site-specific endodeoxyribonucleases specific for altered bases.
based on mapping to UniProt Q96FZ2
3.4.-.-
Acting on peptide bonds (peptidases).
based on mapping to UniProt Q96FZ2

UniProtKB Entries (1)

Q96FZ2
HMCES_HUMAN
Homo sapiens
Abasic site processing protein HMCES

PDB Structure

PDB 5KO9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.
Halabelian, L., Ravichandran, M., Li, Y., Zeng, H., Rao, A., Aravind, L., Arrowsmith, C.H.
Nat.Struct.Mol.Biol.
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