CATH Domain 5knnA01

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Alanine--tRNA ligase, cytoplasmic

6.1.1.7

Alanine--tRNA ligase.

based on mapping to UniProt P49588

ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).

SYAC_HUMAN

Homo sapiens

Alanine--tRNA ligase, cytoplasmic

PDB	5KNN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair. Sun, L., Gomes, A.C., He, W., Zhou, H., Wang, X., Pan, D.W., Schimmel, P., Pan, T., Yang, X.L. J.Am.Chem.Soc.