CATH Domain 5kgxA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.10	Ribonuclease H-like superfamily/Ribonuclease H

Domain Context

CATH Clusters

Superfamily	Ribonuclease H-like superfamily/Ribonuclease H
Functional Family	POL polyprotein

Enzyme Information

UniProtKB Entries (1)

Q76353_9HIV1

Human immunodeficiency virus 1

Integrase

PDB Structure

PDB	5KGX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Indole-based allosteric inhibitors of HIV-1 integrase. Patel, P.A., Kvaratskhelia, N., Mansour, Y., Antwi, J., Feng, L., Koneru, P., Kobe, M.J., Jena, N., Shi, G., Mohamed, M.S., Li, C., Kessl, J.J., Fuchs, J.R. Bioorg.Med.Chem.Lett.