CATH Domain 5ke4A00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.170	Acetylcholine Binding Protein; Chain: A,
	2.70.170.10	Neurotransmitter-gated ion-channel ligand-binding domain

Domain Context

CATH Clusters

Superfamily	Neurotransmitter-gated ion-channel ligand-binding domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q8WSF8_APLCA

Aplysia californica

Soluble acetylcholine receptor

PDB Structure

PDB	5KE4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 6 nicotinic acetylcholine receptor in complex with 2-((5-(3,7-Diazabicyclo[3.3.1]nonan-3-yl)pyridin-3-yl)oxy)- N,N-dimethylethanamine (BPC) Bobango, J., Wu, J., Talley, I.T., Ralston, R., Sankaran, B., Talley, T.T. To Be Published