CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.226 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
|
3.90.226.10 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
| Functional Family | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase |
Enzyme Information
| 1.13.11.80 |
(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase.
based on mapping to UniProt Q8KLK7
(3,5-dihydroxyphenyl)acetyl-CoA + O(2) = 2-(3,5-dihydroxyphenyl)-2- oxoacetate + CoA.
-!- The enzyme, characterized from bacteria Streptomyces toyocaensis and Amycolatopsis orientalis, is involved in the biosynthesis of (3,5- dihydroxyphenyl)glycine, a component of the glycopeptide antibiotic vancomycin.
|
UniProtKB Entries (1)
| Q8KLK7 |
DPGC_STRTO
Streptomyces toyocaensis
(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
|
PDB Structure
| PDB | 5KAG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.
Acta Crystallogr D Struct Biol
|