CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.70 | Alpha-Beta Plaits | |
3.30.70.2840 | Flavivirus RNA-directed RNA polymerase, thumb domain |
Domain Context
CATH Clusters
Superfamily | Flavivirus RNA-directed RNA polymerase, thumb domain |
Functional Family |
Enzyme Information
UniProtKB Entries (1)
A0A097PIE2 |
A0A097PIE2_9FLAV
Dengue virus 2
Genome polyprotein
|
PDB Structure
PDB | 5K5M |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
Plos Pathog.
|