CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.60 | ARID DNA-binding domain |
Domain Context
CATH Clusters
| Superfamily | ARID DNA-binding domain |
| Functional Family | Putative lysine-specific demethylase 5b |
Enzyme Information
| 1.14.11.- |
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt P29375
|
UniProtKB Entries (1)
| P29375 |
KDM5A_HUMAN
Homo sapiens
Lysine-specific demethylase 5A
|
PDB Structure
| PDB | 5K4L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.
Bioorg.Med.Chem.Lett.
|
