CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.390 | Neutral Protease; domain 2 |
|
1.10.390.10 | Neutral Protease Domain 2 |
Domain Context
CATH Clusters
| Superfamily | Neutral Protease Domain 2 |
| Functional Family | Aminopeptidase |
Enzyme Information
| 3.4.11.- |
Aminopeptidases.
based on mapping to UniProt Q6P179
|
UniProtKB Entries (1)
| Q6P179 |
ERAP2_HUMAN
Homo sapiens
Endoplasmic reticulum aminopeptidase 2
|
PDB Structure
| PDB | 5K1V |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.
ACS Med Chem Lett
|