CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.170 | Beta Complex |
|
2.170.220 | Methionyl-trna Synthetase; domain 2 |
|
2.170.220.10 |
Domain Context
CATH Clusters
| Superfamily | 2.170.220.10 |
| Functional Family | methionine--tRNA ligase, mitochondrial |
Enzyme Information
| 6.1.1.10 |
Methionine--tRNA ligase.
based on mapping to UniProt P59078
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).
-!- In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
|
UniProtKB Entries (1)
| P59078 |
SYM_BRUSU
Brucella suis 1330
Methionine--tRNA ligase
|
PDB Structure
| PDB | 5K0T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.
Plos One
|
