CATH Domain 5jcxA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

O76290_TRYBB

Trypanosoma brucei brucei

Pteridine reductase

PDB Structure

PDB	5JCX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs. Borsari, C., Luciani, R., Pozzi, C., Poehner, I., Henrich, S., Trande, M., Cordeiro-da-Silva, A., Santarem, N., Baptista, C., Tait, A., Di Pisa, F., Dello Iacono, L., Landi, G., Gul, S., Wolf, M., Kuzikov, M., Ellinger, B., Reinshagen, J., Witt, G., Gribbon, P., Kohler, M., Keminer, O., Behrens, B., Costantino, L., Tejera Nevado, P., Bifeld, E., Eick, J., Clos, J., Torrado, J., Jimenez-Anton, M.D., Corral, M.J., Alunda, J.M., Pellati, F., Wade, R.C., Ferrari, S., Mangani, S., Costi, M.P. J.Med.Chem.