CATH Classification

Domain Context

CATH Clusters

Superfamily Laminin
Functional Family Coagulation factor VII

Enzyme Information

3.4.21.22
Coagulation factor IXa.
based on mapping to UniProt P00740
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- The proenzyme factor IX is activated by EC 3.4.21.27. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P00740
FA9_HUMAN
Homo sapiens
Coagulation factor IX

PDB Structure

PDB 5JB9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Releasing the brakes in coagulation Factor IXa by co-operative maturation of the substrate-binding site.
Kristensen, L.H., Olsen, O.H., Blouse, G.E., Brandstetter, H.
Biochem.J.