CATH Domain 5jaoA00

Superfamily	alpha/beta hydrolase
Functional Family	Platelet-activating factor acetylhydrolase

3.1.1.47

1-alkyl-2-acetylglycerophosphocholine esterase.

based on mapping to UniProt Q13093

1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl- sn-glycero-3-phosphocholine + acetate.

PAFA_HUMAN

Homo sapiens

Platelet-activating factor acetylhydrolase

PDB	5JAO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening. Woolford, A.J., Pero, J.E., Aravapalli, S., Berdini, V., Coyle, J.E., Day, P.J., Dodson, A.M., Grondin, P., Holding, F.P., Lee, L.Y., Li, P., Manas, E.S., Marino, J., Martin, A.C., McCleland, B.W., McMenamin, R.L., Murray, C.W., Neipp, C.E., Page, L.W., Patel, V.K., Potvain, F., Rich, S., Rivero, R.A., Smith, K., Somers, D.O., Trottet, L., Velagaleti, R., Williams, G., Xie, R. J.Med.Chem.