CATH Domain 5j3lA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.357	Tetracycline Repressor; domain 2
	1.10.357.10	Tetracycline Repressor, domain 2

Domain Context

CATH Clusters

Superfamily	Tetracycline Repressor, domain 2
Functional Family	HTH-type transcriptional regulator EthR

Enzyme Information

UniProtKB Entries (1)

ETHR_MYCTU

Mycobacterium tuberculosis H37Rv

HTH-type transcriptional regulator EthR

PDB Structure

PDB	5J3L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. Nikiforov, P.O., Blaszczyk, M., Surade, S., Boshoff, H.I., Sajid, A., Delorme, V., Deboosere, N., Brodin, P., Baulard, A.R., Barry, C.E., Blundell, T.L., Abell, C. ACS Chem. Biol.