CATH Classification

Domain Context

CATH Clusters

Superfamily Isopropylmalate Dehydrogenase
Functional Family 3-isopropylmalate dehydrogenase

Enzyme Information

1.1.1.85
3-isopropylmalate dehydrogenase.
based on mapping to UniProt P93832
(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO(2) + NADH.

UniProtKB Entries (1)

P93832
LEU32_ARATH
Arabidopsis thaliana
3-isopropylmalate dehydrogenase 2, chloroplastic

PDB Structure

PDB 5J33
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and Mechanism of Isopropylmalate Dehydrogenase from Arabidopsis thaliana: INSIGHTS ON LEUCINE AND ALIPHATIC GLUCOSINOLATE BIOSYNTHESIS.
Lee, S.G., Nwumeh, R., Jez, J.M.
J.Biol.Chem.
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