CATH Domain 5izqG00

Superfamily
Functional Family	-

PDB	5IZQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis. Golani, L.K., Wallace-Povirk, A., Deis, S.M., Wong, J., Ke, J., Gu, X., Raghavan, S., Wilson, M.R., Li, X., Polin, L., de Waal, P.W., White, K., Kushner, J., O'Connor, C., Hou, Z., Xu, H.E., Melcher, K., Dann, C.E., Matherly, L.H., Gangjee, A. J.Med.Chem.