CATH Domain 5iv4A01

Superfamily	Nucleotide cyclase
Functional Family	Adenylate cyclase type 10

4.6.1.1

Adenylate cyclase.

based on mapping to UniProt Q96PN6

ATP = 3',5'-cyclic AMP + diphosphate.

-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.

ADCYA_HUMAN

Homo sapiens

Adenylate cyclase type 10

PDB	5IV4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. Ramos-Espiritu, L., Kleinboelting, S., Navarrete, F.A., Alvau, A., Visconti, P.E., Valsecchi, F., Starkov, A., Manfredi, G., Buck, H., Adura, C., Zippin, J.H., van den Heuvel, J., Glickman, J.F., Steegborn, C., Levin, L.R., Buck, J. Nat.Chem.Biol.