CATH Classification

Domain Context

CATH Clusters

Superfamily Dehydroquinate synthase-like - alpha domain
Functional Family

Enzyme Information

4.2.3.4
3-dehydroquinate synthase.
based on mapping to UniProt Q5NFS1
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate.
-!- The hydrogen atoms on C-7 of the substrate are retained on C-2 of the products. -!- Formerly EC 4.6.1.3.

UniProtKB Entries (1)

Q5NFS1
AROB_FRATT
Francisella tularensis subsp. tularensis SCHU S4
3-dehydroquinate synthase

PDB Structure

PDB 5HVN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
3.0 Angstrom Crystal Structure of 3-dehydroquinate Synthase (AroB) from Francisella tularensis in Complex with NAD.
Minasov, G., Light, S.H., Shuvalova, L., Dubrovska, I., Winsor, J., Zhou, M., Grimshaw, S., Kwon, K., Joachimiak, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
To Be Published