CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.710 | Beta-lactamase |
|
3.40.710.10 | DD-peptidase/beta-lactamase superfamily |
Domain Context
CATH Clusters
| Superfamily | DD-peptidase/beta-lactamase superfamily |
| Functional Family | glutaminase kidney isoform, mitochondrial |
Enzyme Information
| 3.5.1.2 |
Glutaminase.
based on mapping to UniProt O94925
L-glutamine + H(2)O = L-glutamate + NH(3).
|
UniProtKB Entries (1)
| O94925 |
GLSK_HUMAN
Homo sapiens
Glutaminase kidney isoform, mitochondrial
|
PDB Structure
| PDB | 5HL1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the clinically relevant glutaminase inhibitot CB-839 in complex with glutaminase C
To Be Published
|