CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.238.210
Functional Family Glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2
Glutaminase.
based on mapping to UniProt O94925
L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

O94925
GLSK_HUMAN
Homo sapiens
Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB 5HL1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the clinically relevant glutaminase inhibitot CB-839 in complex with glutaminase C
Huang, Q., Katt, W.P., McDermott, L.A., Cerione, R.A.
To Be Published
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