CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family Polycomb protein eed

Enzyme Information

UniProtKB Entries (1)

O75530
EED_HUMAN
Homo sapiens
Polycomb protein EED

PDB Structure

PDB 5H24
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy
Huang, Y., Zhang, J., Yu, Z., Zhang, H., Wang, Y., Lingel, A., Qi, W., Gu, J., Zhao, K., Shultz, M.D., Wang, L., Fu, X., Sun, Y., Zhang, Q., Jiang, X., Zhang, J., Zhang, C., Li, L., Zeng, J., Feng, L., Zhang, C., Liu, Y., Zhang, M., Zhang, L., Zhao, M., Gao, Z., Liu, X., Fang, D., Guo, H., Mi, Y., Gabriel, T., Dillon, M.P., Atadja, P., Oyang, C.
J. Med. Chem.