CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Structural polyprotein

Enzyme Information

3.4.21.90
Togavirin.
based on mapping to UniProt P0DOK1
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
-!- Once released, the core protein does not retain catalytic activity. -!- Belongs to peptidase family S3.

UniProtKB Entries (1)

P0DOK1
POLSF_CHIKS
Chikungunya virus strain S27-African prototype
Frameshifted structural polyprotein

PDB Structure

PDB 5H23
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-function insights into chikungunya virus capsid protein: Small molecules targeting capsid hydrophobic pocket.
Sharma, R., Kesari, P., Kumar, P., Tomar, S.
Virology