CATH Classification
Domain Context
CATH Clusters
| Superfamily | Nitric Oxide Synthase; Chain A, domain 3 |
| Functional Family | Nitric oxide synthase, brain |
Enzyme Information
| 1.14.14.47 |
Nitric-oxide synthase (flavodoxin).
based on mapping to UniProt O34453
2 L-arginine + 3 reduced flavodoxin + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H(2)O.
-!- The enzyme, found in bacteria and archaea, consist of only an oxygenase domain and functions together with bacterial ferredoxins or flavodoxins. -!- The orthologous enzymes from plants and animals also contain a reductase domain and use only NADPH as the electron donor (cf. EC 1.14.13.39). -!- Formerly EC 1.14.13.165.
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UniProtKB Entries (1)
| O34453 |
NOSO_BACSU
Bacillus subtilis subsp. subtilis str. 168
Nitric oxide synthase oxygenase
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PDB Structure
| PDB | 5G6A |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors.
Biochemistry
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