CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Putative lysine-specific demethylase 5b

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q9UGL1

UniProtKB Entries (1)

Q9UGL1
KDM5B_HUMAN
Homo sapiens
Lysine-specific demethylase 5B

PDB Structure

PDB 5FZA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with 3D Fragment 2-Piperidin-4-Yloxy-5-(Trifluoromethyl)Pyridine (N10072A) (Ligand Modelled Based on Pandda Event Map)
Nowak, R., Krojer, T., Pearce, N., Johansson, C., Gileadi, C., Kupinska, K., Strain-Damerell, C., Szykowska, A., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., von Delft, F., Brennan, P.E., Oppermann, U.
To be Published
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