CATH Domain 5fh8A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	protein polybromo-1 isoform X1

Enzyme Information

UniProtKB Entries (1)

PB1_HUMAN

Homo sapiens

Protein polybromo-1

PDB Structure

PDB	5FH8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex. Sutherell, C.L., Tallant, C., Monteiro, O.P., Yapp, C., Fuchs, J.E., Fedorov, O., Siejka, P., Muller, S., Knapp, S., Brenton, J.D., Brennan, P.E., Ley, S.V. J.Med.Chem.