CATH Classification

Domain Context

CATH Clusters

Superfamily Blc2-like
Functional Family Induced myeloid leukemia cell differentiation protein Mcl-1

Enzyme Information

UniProtKB Entries (1)

Q07820
MCL1_HUMAN
Homo sapiens
Induced myeloid leukemia cell differentiation protein Mcl-1

PDB Structure

PDB 5FDR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods.
Pelz, N.F., Bian, Z., Zhao, B., Shaw, S., Tarr, J.C., Belmar, J., Gregg, C., Camper, D.V., Goodwin, C.M., Arnold, A.L., Sensintaffar, J.L., Friberg, A., Rossanese, O.W., Lee, T., Olejniczak, E.T., Fesik, S.W.
J.Med.Chem.
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