CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.437 | Apoptosis Regulator Bcl-x | |
1.10.437.10 | Blc2-like |
Domain Context
CATH Clusters
Superfamily | Blc2-like |
Functional Family | Induced myeloid leukemia cell differentiation protein Mcl-1 |
Enzyme Information
UniProtKB Entries (1)
Q07820 |
MCL1_HUMAN
Homo sapiens
Induced myeloid leukemia cell differentiation protein Mcl-1
|
PDB Structure
PDB | 5FDO |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods.
J.Med.Chem.
|