CATH Classification
Level | CATH Code | Description |
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1 | Mainly Alpha |
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1.20 | Up-down Bundle |
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1.20.1320 | phosphoenolpyruvate carboxylase, domain 3 |
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1.20.1320.30 |
Domain Context
CATH Clusters
Superfamily | 1.20.1320.30 |
Functional Family | Probable ATP-dependent RNA helicase DDX58 |
Enzyme Information
3.6.4.13 |
RNA helicase.
based on mapping to UniProt O95786
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).
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UniProtKB Entries (1)
O95786 |
DDX58_HUMAN
Homo sapiens
Probable ATP-dependent RNA helicase DDX58
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PDB Structure
PDB | 5F98 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc.Natl.Acad.Sci.USA
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