CATH Domain 5f59A00

Superfamily	SET domain
Functional Family	Histone-lysine N-methyltransferase

2.1.1.43

Histone-lysine N-methyltransferase.

based on mapping to UniProt Q8NEZ4

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

KMT2C_HUMAN

Homo sapiens

Histone-lysine N-methyltransferase 2C

PDB	5F59
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for activity regulation of MLL family methyltransferases. Li, Y., Han, J., Zhang, Y., Cao, F., Liu, Z., Li, S., Wu, J., Hu, C., Wang, Y., Shuai, J., Chen, J., Cao, L., Li, D., Shi, P., Tian, C., Zhang, J., Dou, Y., Li, G., Chen, Y., Lei, M. Nature