CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.42.10
Functional Family Tyrosine-protein phosphatase non-receptor type

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P29074
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

B5MDL5
B5MDL5_HUMAN
Homo sapiens
Mitogen-activated protein kinase

PDB Structure

PDB 5EZ0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
Maisonneuve, P., Caillet-Saguy, C., Vaney, M.C., Bibi-Zainab, E., Sawyer, K., Raynal, B., Haouz, A., Delepierre, M., Lafon, M., Cordier, F., Wolff, N.
J.Biol.Chem.
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