CATH Classification

Domain Context

CATH Clusters

Superfamily Multidrug efflux transporter AcrB pore domain
Functional Family Efflux pump membrane transporter

Enzyme Information

UniProtKB Entries (1)

P31224
ACRB_ECOLI
Escherichia coli K-12
Multidrug efflux pump subunit AcrB

PDB Structure

PDB 5ENQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
Sjuts, H., Vargiu, A.V., Kwasny, S.M., Nguyen, S.T., Kim, H.S., Ding, X., Ornik, A.R., Ruggerone, P., Bowlin, T.L., Nikaido, H., Pos, K.M., Opperman, T.J.
Proc.Natl.Acad.Sci.USA