CATH Domain 5elxA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	ATP-dependent RNA helicase DBP5

Enzyme Information

3.6.4.13

RNA helicase.

based on mapping to UniProt A6ZNQ1

ATP + H(2)O = ADP + phosphate.

-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

A6ZNQ1

DBP5_YEAS7

Saccharomyces cerevisiae YJM789

ATP-dependent RNA helicase DBP5

PDB Structure

PDB	5ELX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Pi Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5). Wong, E.V., Cao, W., Voros, J., Merchant, M., Modis, Y., Hackney, D.D., Montpetit, B., De La Cruz, E.M. J.Mol.Biol.