CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleic acid-binding proteins
Functional Family Lysine--tRNA ligase

Enzyme Information

UniProtKB Entries (1)

Q5CR27
Q5CR27_CRYPI
Cryptosporidium parvum Iowa II
Lysine--tRNA ligase

PDB Structure

PDB 5ELO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Baragana, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J.A., Pisco, J.P., Peet, C., Dranow, D.M., Robinson, D.A., Jansen, C., Norcross, N.R., Vinayak, S., Anderson, M., Brooks, C.F., Cooper, C.A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T.E., Hallyburton, I., Horst, B.G., Hulverson, M.A., Ferguson, L., Jimenez-Diaz, M.B., Jumani, R.S., Lorimer, D.D., Love, M.S., Maher, S., Matthews, H., McNamara, C.W., Miller, P., O'Neill, S., Ojo, K.K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L.M., Scullion, P., Sharma, A., Shepherd, S.M., Shishikura, Y., Simeons, F.R.C., Stebbins, E.E., Stojanovski, L., Straschil, U., Tamaki, F.K., Tamjar, J., Torrie, L.S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F.J., Maser, P., Kyle, D.E., Winzeler, E.A., Myler, P.J., Wyatt, P.G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C.D., Gray, D.W., Fairlamb, A.H., Pisliakov, A.V., Walpole, C., Read, K.D., Van Voorhis, W.C., Gilbert, I.H.
Proc. Natl. Acad. Sci. U.S.A.
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