CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.760 | RNA Cap, Translation Initiation Factor Eif4e |
|
3.30.760.10 | RNA Cap, Translation Initiation Factor Eif4e |
Domain Context
CATH Clusters
| Superfamily | RNA Cap, Translation Initiation Factor Eif4e |
| Functional Family | Eukaryotic translation initiation factor 4E |
Enzyme Information
UniProtKB Entries (1)
| P06730 |
IF4E_HUMAN
Homo sapiens
Eukaryotic translation initiation factor 4E
|
PDB Structure
| PDB | 5EKV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation.
Eur.J.Med.Chem.
|
