CATH Domain 5eddA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.40	Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A
	2.70.40.10	Deoxyuridine triphosphatase (dUTPase)

Domain Context

CATH Clusters

Superfamily	2.70.40.10
Functional Family	Deoxyuridine 5'-triphosphate nucleotidohydrolase

Enzyme Information

3.6.1.23

dUTP diphosphatase.

based on mapping to UniProt P9WNS5

dUTP + H(2)O = dUMP + diphosphate.

UniProtKB Entries (1)

DUT_MYCTU

Mycobacterium tuberculosis H37Rv

Deoxyuridine 5'-triphosphate nucleotidohydrolase

PDB Structure

PDB	5EDD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases. Nagy, G.N., Suardiaz, R., Lopata, A., Ozohanics, O., Vekey, K., Brooks, B.R., Leveles, I., Toth, J., Vertessy, B.G., Rosta, E. J. Am. Chem. Soc.