CATH Classification
Level | CATH Code | Description |
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2 | Mainly Beta |
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2.30 | Roll |
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2.30.30 | SH3 type barrels. |
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2.30.30.40 | SH3 Domains |
Domain Context
CATH Clusters
Superfamily | SH3 Domains |
Functional Family |
Enzyme Information
2.7.10.2 |
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P00523
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.
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UniProtKB Entries (1)
P00523 |
SRC_CHICK
Gallus gallus
Proto-oncogene tyrosine-protein kinase Src
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PDB Structure
PDB | 5EC7 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of a chimeric c-Src-SH3 domain with the sequence of the RT-loop from the Abl-SH3 domain at pH 5.0
to be published
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