CATH Classification

Domain Context

CATH Clusters

Superfamily Farnesyl Diphosphate Synthase
Functional Family Geranylgeranyl diphosphate synthase

Enzyme Information

2.5.1.1
Dimethylallyltranstransferase.
based on mapping to UniProt P34802
Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
-!- Will not accept larger prenyl diphosphates as efficient donors.
2.5.1.10
(2E,6E)-farnesyl diphosphate synthase.
based on mapping to UniProt P34802
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)- farnesyl diphosphate.
-!- Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. -!- The enzyme will not accept larger prenyl diphosphates as efficient donors.
2.5.1.-
Transferring alkyl or aryl groups, other than methyl groups.
based on mapping to UniProt P34802
2.5.1.29
Geranylgeranyl diphosphate synthase.
based on mapping to UniProt P34802
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
-!- Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.

UniProtKB Entries (1)

P34802
GGPP1_ARATH
Arabidopsis thaliana
Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplastic

PDB Structure

PDB 5E8L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants.
Wang, C., Chen, Q., Fan, D., Li, J., Wang, G., Zhang, P.
Mol Plant