CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.600 | Farnesyl Diphosphate Synthase |
|
1.10.600.10 | Farnesyl Diphosphate Synthase |
Domain Context
CATH Clusters
| Superfamily | Farnesyl Diphosphate Synthase |
| Functional Family | Geranylgeranyl diphosphate synthase |
Enzyme Information
| 2.5.1.10 |
(2E,6E)-farnesyl diphosphate synthase.
based on mapping to UniProt Q9LJY2
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)- farnesyl diphosphate.
-!- Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. -!- The enzyme will not accept larger prenyl diphosphates as efficient donors.
|
| 2.5.1.1 |
Dimethylallyltranstransferase.
based on mapping to UniProt Q9LJY2
Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
-!- Will not accept larger prenyl diphosphates as efficient donors.
|
| 2.5.1.- |
Transferring alkyl or aryl groups, other than methyl groups.
based on mapping to UniProt Q9LJY2
|
| 2.5.1.29 |
Geranylgeranyl diphosphate synthase.
based on mapping to UniProt Q9LJY2
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
-!- Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.
|
UniProtKB Entries (1)
| Q9LJY2 |
GGPPA_ARATH
Arabidopsis thaliana
Geranylgeranyl pyrophosphate synthase 10, mitochondrial
|
PDB Structure
| PDB | 5E8K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants.
Mol Plant
|
