CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.540 | Fructose-1,6-Bisphosphatase; Chain A, domain 1 |
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3.30.540.30 |
Domain Context
CATH Clusters
Superfamily | 3.30.540.30 |
Functional Family | Dipeptidyl peptidase 3 |
Enzyme Information
3.4.14.4 |
Dipeptidyl-peptidase III.
based on mapping to UniProt Q9NY33
Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.
-!- A cytosolic peptidase that is active at neutral pH. -!- It has broad activity on peptides, although it is highly selective for Arg-Arg-2-naphthylamide, at pH 9.2. -!- Active in the hydrolysis of enkephalins. -!- Belongs to peptidase family M49.
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UniProtKB Entries (1)
P01019 |
ANGT_HUMAN
Homo sapiens
Angiotensinogen
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PDB Structure
PDB | 5E2Q |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.
Sci Rep
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