CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | 12-oxophytodienoate reductase 3 |
Enzyme Information
| 1.3.1.92 |
Artemisinic aldehyde Delta(11(13)) reductase.
based on mapping to UniProt C5H429
(11R)-dihydroartemisinic aldehyde + NADP(+) = artemisinic aldehyde + NADPH.
-!- Cloned from Artemisia annua. -!- In addition to the reduction of artemisinic aldehyde it is also able to a lesser extent to reduce artemisinic alcohol and artemisinic acid. -!- Part of the biosyntheis of artemisinin.
|
UniProtKB Entries (1)
| C5H429 |
DBR2_ARTAN
Artemisia annua
Artemisinic aldehyde Delta(11(13)) reductase
|
PDB Structure
| PDB | 5DXY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Crystal structure of Dbr2
to be published
|
