CATH Domain 5dw2A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

BRD4_HUMAN

Homo sapiens

Bromodomain-containing protein 4

PDB Structure

PDB	5DW2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	RVX-297- a novel BD2 selective inhibitor of BET bromodomains. Kharenko, O.A., Gesner, E.M., Patel, R.G., Norek, K., White, A., Fontano, E., Suto, R.K., Young, P.R., McLure, K.G., Hansen, H.C. Biochem.Biophys.Res.Commun.