CATH Domain 5dkhA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	probable global transcription activator SNF2L2 isoform X1

Enzyme Information

3.6.4.-

Acting on ATP; involved in cellular and subcellular movement.

based on mapping to UniProt P51531

UniProtKB Entries (1)

SMCA2_HUMAN

Homo sapiens

Probable global transcription activator SNF2L2

PDB Structure

PDB	5DKH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a hydroxyphenyl propenone inhibitor 17 Tallant, C., Owen, D.R., Taylor, A., Fedorov, O., Savitsky, P., Siejka, P., Srikannathasan, V., Nowak, R., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S. To Be Published