CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.200 | Tumour Suppressor Smad4 |
|
2.60.200.30 | Probable inorganic polyphosphate/atp-NAD kinase; domain 2 |
Domain Context
CATH Clusters
| Superfamily | Probable inorganic polyphosphate/atp-NAD kinase; domain 2 |
| Functional Family | NAD kinase |
Enzyme Information
| 2.7.1.23 |
NAD(+) kinase.
based on mapping to UniProt Q8Y8D7
ATP + NAD(+) = ADP + NADP(+).
|
UniProtKB Entries (1)
| Q8Y8D7 |
NADK1_LISMO
Listeria monocytogenes EGD-e
NAD kinase 1
|
PDB Structure
| PDB | 5DHP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode.
Eur.J.Med.Chem.
|