CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.10 | D-amino Acid Aminotransferase; Chain A, domain 2 |
|
3.20.10.10 | D-amino Acid Aminotransferase, subunit A, domain 2 |
Domain Context
CATH Clusters
| Superfamily | D-amino Acid Aminotransferase, subunit A, domain 2 |
| Functional Family | D-alanine aminotransferase |
Enzyme Information
| 2.6.1.21 |
D-amino-acid transaminase.
based on mapping to UniProt P19938
D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.
-!- The enzyme from thermophilic Bacillus species acts on many D-amino acids with D-alanine and D-2-aminobutyrate as the best amino donors. -!- It can similarly use any of several 2-oxo acids as amino acceptor, with 2-oxoglutarate and 2-oxobutyrate among the best. -!- The enzyme from some other sources has a broader specificity. -!- Formerly EC 2.6.1.10.
|
UniProtKB Entries (1)
| P19938 |
DAAA_BACYM
Bacillus sp. YM-1
D-alanine aminotransferase
|
PDB Structure
| PDB | 5DAA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Effects of the E177K mutation in D-amino acid transaminase. Studies on an essential coenzyme anchoring group that contributes to stereochemical fidelity.
Biochemistry
|
